Bitcoin DeFi key to unlocking $300T potential: Asymmetric Founder

On Supply Shock, Asymmetric founder Dan Held discussed why Bitcoin DeFi will take market share from Solana, Ethereum and other top blockchains

article-image

bovall/Shutterstock modified by Blockworks

share


This is a segment from the Supply Shock newsletter. To read full editions, subscribe


Serial entrepreneur Dan Held, whose past exits include Zeroblock and Interchange, sees Bitcoin DeFi as the largest untapped opportunity of his decade-long crypto career.

Speaking on the Supply Shock podcast Tuesday, Held told host Pete Rizzo that he sees decentralized finance (DeFi) as the key to unlocking bitcoin’s potential as a $300 trillion global asset. He pointed to the ability to earn yield for lending bitcoin — one of the many financial functions DeFi replicates without centralized intermediaries — as a major opportunity.

Held’s journey into Bitcoin DeFi began with his exploration of yield-generating opportunities, including providing liquidity for Lightning channels and Coinjoins. Initially skeptical of DeFi due to its association with scams, Held became convinced of its potential after witnessing new use cases on alternative crypto platforms like Ethereum and Solana.

He noted that DeFi could introduce new users to bitcoin, much like early adopters were drawn in through activities like Silk Road and speculation. “If DeFi could be unlocked on Bitcoin, it would be by far the biggest opportunity ever to happen in crypto,” Held said.

Elsewhere, Held told Rizzo he does not see Bitcoin DeFi as a zero-sum game where Bitcoin replaces other blockchains entirely. “I think what will happen is that this just absorbs market share from the other ones significantly, but not totally, and that this increases Bitcoin’s dominance,” Held explained. 

“I think Bitcoin dominance goes up if DeFi and Bitcoin gets unlocked…because in doing so, it locks up a lot of bitcoin. It also drives more demand to buy bitcoin. And so I think all of that’s good for Bitcoin,” he continued. 

Held recently co-founded Asymmetric with Joe McCann. The venture capital firm’s portfolio includes Bitcoin DeFi startups such as Liquidium, Fractal and BitLayer.

The addition of DeFi opportunities to Bitcoin is not without its challenges. Held noted Bitcoin’s user experience must compete with Solana, which offers low-cost transactions. However, Held believes that Bitcoin’s L2 solutions will play a crucial role in enhancing user experience, offering performance similar to Ethereum and Solana. 

“I think there’s going to be this renaissance in the Bitcoin DeFi world [in 2025],” Held said.

Updated March 11, 2025 at 1:59 pm ET: Added mention of Asymmetric co-founder.


Get the news in your inbox. Explore Blockworks newsletters:

Tags

Decoding crypto and the markets. Daily, with Byron Gilliam.

Upcoming Events

Old Billingsgate

Mon - Wed, October 13 - 15, 2025

Blockworks’ Digital Asset Summit (DAS) will feature conversations between the builders, allocators, and legislators who will shape the trajectory of the digital asset ecosystem in the US and abroad.

recent research

Research Report Templates.jpg

Research

Figure, founded by former SoFi CEO Mike Cagney, has emerged as a leader in onchain RWAs, with ~$17.5B publicly tokenized. The platform’s ecosystem volume is growing ~40% YoY as it expands beyond HELOCs into student loans, DSCR loans, unsecured loans, bankruptcy claims, and more. Operationally, Figure cuts average loan production cost by ~93% and compresses median funding time from ~42 days to ~10, creating a durable speed-and-cost advantage.

article-image

The Ethereum co-founder suggested LINEA holders would be eligible for other airdrops in cryptic tweet

article-image

The layer-2’s biggest release yet brings benefits — but a post-upgrade outage caused a chain reorg

article-image

Crypto is shifting into risk-on mode — pump.fun dominates meme activity, while Lido leans on treasury maneuvers

article-image

If the president breaks the Fed, he’ll own the budget problems

article-image

Combining Franklin Templeton’s tokenization expertise with Binance’s trading infrastructure could speed crypto adoption, companies say

article-image

The firm’s upcoming filing comes as competition heats up over the USDH stablecoin